Trileptal treatment trigeminal neuralgia

There is no increase in the total rate of malformations with trileptal as compared with the rate observed in the general population 2-3 .
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pMusculoskeletalconnective tissue and bone disordersThere have been reports of decreased bone mineral densityosteoporosis and fractures in patients on long-term therapy with TRILEPTAL./ppAlthough this study failed to demonstrate an effect of oxcarbazepine as monotherapy in pediatric patientsseveral design elementsincluding the short treatment and assessment periodthe absence of a true placeboand the likely persistence of plasma levels of previously administered AEDs during the treatment periodmake the results uninterpretableFor this reasonthe results do not undermine the conclusionbased on pharmacokinetic/pharmacodynamic considerationsthat oxcarbazepine is effective as monotherapy in pediatric patients 4 years old and older./ppDrug Reaction With Eosinophilia And Systemic SymptomsDRESSMulti-Organ Hypersensitivity./ppAGenerally acceptableControlled studies in pregnant women show no evidence of fetal risk./ppIt is not known if TRILEPTAL is safe and effective for use alone to treat partial seizures in children less than 4 years of age or for use with other medicines to treat partial seizures in children less than 2 years of age./p

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