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pDrugs which may affect leukocyte productionincluding cotrimoxazolemay lead to exaggerated leukopeniaespecially in renal transplant recipients./ppA gastrointestinal hypersensitivity reaction characterized by severe nausea and vomiting has been reportedThese symptoms may also be accompanied by diarrhearashfevermalaisemyalgiaselevations in liver enzymesand occasionallyhypotensionSymptoms of gastrointestinal toxicity most often develop within the first several weeks of therapy with IMURAN and are reversible upon discontinuation of the drugThe reaction can recur within hours after re-challenge with a single dose of IMURAN./ppAlways consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances./p

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