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pAvoid making any changes in your diet without first talking to your doctorSome foods can make warfarin less effective./ppAvoid making any changes in your diet without first talking to your doctorSome foods can make warfarin less effective./ppTrials in patients with both AF and mitral stenosis suggest a benefit from anticoagulation with COUMADINsee DOSAGE AND ADMINISTRATION/ppCOUMADIN can cause major or fatal bleedingsee WARNINGS AND PRECAUTIONSPerform regular monitoring of INR in all treated patientssee DOSAGE AND ADMINISTRATIONDrugsdietary changesand other factors affect INR levels achieved with COUMADIN therapysee DRUG INTERACTIONSInstruct patients about prevention measures to minimize risk of bleeding and to report signs and symptoms of bleedingsee PATIENT INFORMATION/ppSome side effects of warfarin may occur that usually do not need medical attentionThese side effects may go away during treatment as your body adjusts to the medicineAlsoyour health care professional may be able to tell you about ways to prevent or reduce some of these side effectsCheck with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:/p

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