Tamoxifen citrate has a molecular weight of 563.
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006 for time to tumor progression; objective tumor response rates were similar for arimidex and tamoxifen.
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research suggests that long-term use of tamoxifen among post-menopausal women increases the chances of endometrial problems.
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ovarian cysts have also been observed in a small number of premenopausal patients with advanced breast cancer who have been treated with tamoxifen.
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the mice were administered the trans and racemic forms of tamoxifen for 13 to 15 months at doses of 5, 20 and 50 mg kg day about one-half, two and five-fold the daily recommended human dose on a mg m 2 basis .
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a similar increased incidence in endometrial adenocarcinoma and uterine sarcoma was observed among women receiving tamoxifen in five other nsabp clinical trials.
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