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Labetalol, the main active ingredient of trandat, an a-blocker, is 2-7 times less potent than phentolamine regitin , and as a b-blocker it is 5-18 times less potent than propranolol; these facts promote the wide use of preparation.
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i take 120mg of propranolol a day, along with 70mg of amtriptylin due to cluster migraines.
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use propranolol with caution in patients with hepatic disease, because of possible decreased clearance of the drug; reduced doses may be indicated see dosage .
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propranolol, in a dosage of 20 mg or 40 mg, taken an hour or two before a speech, can be helpful in reducing stage anxiety or at times for social phobia.

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